The American Chestnut dominated the Appalachian landscape, ranging from Georgia all the way to Maine. In the late 1800’s a pathogen imported on a tree to the Bronx Zoo spread rapidly into wild populations, destroying millions of trees, and radically changing the forest. There are natural sources of resistance to the pathogen that are being introduced to the American Chestnut with traditional breeding. Transgenic solutions have also been developed. Dr. Jared Westbrook is leading breeding efforts to integrate the multiple types of resistance with the hopes of restoring this important tree in North American ecology. # COLABRA Talking Biotech is brought to you by Colabra – an R&D platform that brings your lab’s world-changing research together in one shared space. Learn more at https://www.colabra.app/ # TALKING BIOTECH Twitter: https://twitter.com/talkingbiotech Website: https://www.colabra.app/podcasts/talking-biotech/ Instagram: https://www.instagram.com/colabrahq The Talking Biotech podcast is distinct from Dr. Kevin Folta's teaching and research roles at the University of Florida. The views expressed on the show are those of Dr. Folta and his guests, and do not reflect the opinions of the university or Colabra.